#1 Choice of Vets¹

Potentially deadly heartworm disease is a threat no matter where you live. Just one bite from an infected mosquito can transmit larvae to your dog that can eventually cause severe damage—and even death. Fight back with HEARTGARD® Plus (ivermectin/pyrantel). Our real-beef chewables help prevent heartworm disease in dogs and puppies 6 weeks of age or older. See how we compare

Discover how
Find the dose that’s right for your dog*

*For use in dogs only

heartworm life span
A dangerous timeline

From the moment an infected mosquito bites your dog, in less than 3 months, young, adult worms reach the vessels of the lungs and can cause permanent damage. The diagrams below show how they grow and affect your dog—and how HEARTGARD Plus stops them.

Infection

A bite from an infected mosquito transmits heartworm larvae to your dog.

Bloodstream

At 3 months, the larvae enter the bloodstream and travel to the pulmonary artery. 

lungs

At 6 months, the now adult heartworms begin to grow in the lungs.

Heart

Left untreated, heartworms can cause damage to the heart and other vital organs.

Infection

A bite from an infected mosquito transmits heartworm larvae to your dog.

Stops

HEARTGARD Plus actually kills the developing larvae before they get to the bloodstream.

prevents

HEARTGARD Plus prevents the larvae from developing into adult heartworms.

Healthy

Your dog’s heart and lungs remain healthy and undamaged. 

Without heartgard
with heartgard
IMPORTANT SAFETY INFORMATION:

HEARTGARD Plus (ivermectin/pyrantel) is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurological side effects have rarely been reported. For more information, contact your veterinarian or click here for full prescribing information.

PROACTIVE PROTECTION

The best treatment is prevention

Treatment for heartworm disease can be risky, expensive, and often involve hospital stays that can be traumatic, especially for puppies. Instead, proactive prevention of heartworm disease can save you money over the long run and keep your dog or puppy2 happy at home where they belong. Heartgard is safe for puppies 6 weeks of age or older.

Easy to give
1. Ask your vet to test for heartworm disease
2. Get HEARTGARD Plus, tasty protection dogs love
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3. Give your dog a real-beef chew every month
IMPORTANT SAFETY INFORMATION:

HEARTGARD Plus (ivermectin/pyrantel) is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurological side effects have rarely been reported. For more information, contact your veterinarian or click here for full prescribing information.

Lady jogging with dog
How we compare

#1 vet-recommended heartworm disease prevention1

Frequently asked questions

Heartworm disease in dogs (dirofilariasis) is a serious and potentially fatal disease. Heartworms spend their adult lives in the pulmonary arteries. The adult worms can cause lasting damage to the heart, lungs, and arteries.

Heartworms are transmitted from one dog to another by mosquitoes, which pick up tiny immature heartworms, called microfilariae, when they bite an infected dog. Larvae develop in the mosquito and then are transmitted to another dog when that dog is bitten by the infective mosquito.

All dogs are at risk for heartworm disease, no matter where they live—heartworms don't discriminate based on geography. In the past, heartworm disease in the United States was primarily limited to the South and Southeast regions. However, it is now found in all 50 states, in Canada, and is spreading to new areas each year.2 The American Heartworm Society notes that uncared-for dogs and certain wildlife can be carriers of heartworms. Mosquitoes blown great distances by the wind and the transportation of infected pets to different geographic locations can all contribute to the spread of heartworm disease.2

Get monthly reminders

Never forget to give your dog their monthly dose with a helpful reminder.

Find a vet near you

The heartworm protection you need is only available with a vet’s prescription.

IMPORTANT SAFETY INFORMATION:

HEARTGARD Plus (ivermectin/pyrantel) is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurological side effects have rarely been reported. For more information, contact your veterinarian or click here for full prescribing information.