women with dog
women with dog

Heartworm Disease: Easily Contracted, Potentially Deadly

Just one bite from an infected mosquito could put your pet at risk for heartworm disease—a serious condition that can cause heart failure, permanent damage to your pet's lungs, and even death. Treating heartworm disease is costly and complicated.1 But prevention is simple. Trust #1 vet-recommended HEARTGARD® Plus (ivermectin/pyrantel) to prevent heartworm disease before it starts.2

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Prevents Heartworm Disease Before It Happens

HEARTGARD Plus attacks heartworm larvae before they can grow into adults and cause heartworm disease.

Year-Round Protection

When given every 30 days, HEARTGARD Plus keeps your dog protected from heartworm disease.

Safe for Puppies, Too

HEARTGARD Plus prevents heartworm disease in dogs as young as 6 weeks of age with no minimum weight requirement.

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Understanding the Threat

  • One bite from an infected mosquito can put your dog at risk
  • HEARTGARD Plus eliminates heartworm larvae before they cause harm
  • Prevent heartworm disease by giving your dog HEARTGARD Plus every month
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Get Prevention From Your Vet

HEARTGARD Plus is #1 vet-recommended for a reason.2 Once your dog has a negative heartworm test and prescription from your vet, you can purchase HEARTGARD Plus in clinic or through their online store.
Use the search tool below to get started.

All Dogs Need Heartworm Disease Prevention

Inside or out, and year-round, all dogs are at risk for heartworm disease and cases have been reported in all 50 states.3,4 Both the American Heartworm Society and CAPC recommend year-round use of a preventive, like #1 vet-recommended HEARTGARD Plus.2

heartworm desease risk map
heartworm desease risk map

Puppies Need Protection Too

Cuteness is no defense against heartworm disease. The American Heartworm Society recommends that puppies get started on a heartworm disease preventive as early as the product label allows.5 And because you need a prescription from your vet for a heartworm disease preventive, talk to them about HEARTGARD Plus—the real-beef chew that’s safe for puppies as young as 6 weeks of age with no minimum weight requirement. 

women with dog
women with dog

Year-Round Protection Is Essential

The American Heartworm Society recommends giving your dog year-round protection. That’s because the threat of heartworm disease doesn’t stop with dropping temperatures.3 Many pet  owners might assume that they only need to give their dog heartworm disease preventives when it’s warm. While heartworm transmission can decrease in winter months, the risk never reaches zero.6 What’s more, on-again, off-again heartworm disease protection is unreliable and can leave your dog with gaps in protection that make him vulnerable to heartworm disease.

boy with dog on grass
boy with dog on grass

Protect your dog against the invisible threat.

Three Tips for Preventing Heartworm Disease

Reduce Mosquito Exposure

Avoid bites to reduce risk. Eliminate standing water where mosquitoes can breed, avoid known mosquito habitats, and limit outdoor exposure during peak mosquito feeding times (dawn and dusk).

Use Preventive Medicine Year-Round

Monthly administration of a preventive, like HEARTGARD Plus, safely and effectively prevents heartworm disease by eliminating heartworm larvae before they can grow into dangerous adult heartworms.

Get Your Dog Tested Every Year

Before getting a prescription for a heartworm disease preventive, your dog must be tested for heartworms. Talk to your vet about testing options.

Hookworms and Roundworms Are Unexpected Threats

Your dog can get hookworms and roundworms by stepping in contaminated soil at the park or ingesting them in your own backyard. Luckily, HEARTGARD Plus treats and controls three species of hookworms and two species of roundworms. 

Learn why there’s more to love in the only real-beef chew.

Veterinarian with a dog Veterinarian with a dog
I have been using HEARTGARD Plus for over twenty years to prevent heartworm disease and control intestinal parasites in my patients. It has been proven to not only be a safe and effective preventive, but it is also a joy to administer as it is a tasty beef chew.
Joseph Zuckerman, DVM


Protect With Two
SAVE $75‡
Nexgard and HEARTGARD PACKAGE next to each other NEXGARD and heartgard packages next to each other
Save Big When You Buy Two
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Get a $75 rebate on your qualifying purchases of either NexGard® (afoxolaner) or a FRONTLINE® Brand Product and HEARTGARD® Plus (ivermectin/pyrantel). Download and present this coupon to your vet. 

Save on Prevention
HEARTGARD PACKAGE with black and white dog HEARTGARD PACKAGE with black and white dog
Get Your Rebate
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Buy 12 doses of HEARTGARD® Plus (ivermectin/pyrantel) and enjoy a $15 rebate: Simply download the coupon and take it to your vet.

Know the Signs of Heartworm Disease

Heartworm disease is a potentially fatal threat for dogs—knowing the signs is important to keep your dog safe. Get to know a little more about the signs and treatment of heartworm disease.

Fleas and ticks are threats to your dog, too. Pair up HEARTGARD Plus with powerful flea and tick protection.