small dog with owner
small dog with owner

Don’t risk it. Get heartworm prevention today.

Heartworm disease is a potentially deadly year-round threat. To protect your dog with HEARTGARD® Plus (ivermectin/pyrantel), you need a heartworm test and a prescription from your vet.

Find Your Vet

For puppies 6 weeks of age and older


HEARTGARD Plus (ivermectin/pyrantel) is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurological side effects have rarely been reported. For more information, contact your veterinarian or click here for full prescribing information.

image of both Heartgard and NexGard products
The perfect pair for
powerful protection

HEARTGARD Plus works seamlessly with
NexGard® (afoxolaner), the #1 vet-recommended flea and tick protection.2 Protect your dog with two convenient monthly chews.


NexGard (afoxolaner) is for use in dogs only. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, click here for full prescribing information.