The risk is real

Prevent life-threatening heartworm disease 

Just ONE bite from an infected mosquito can transmit potentially deadly heartworm disease. Don’t take a chance with your dog’s health. Protect your dog year-round with HEARTGARD® Plus (ivermectin/pyrantel), the brand veterinarians recommend most.


For puppies 6 weeks of age and older

The #1 Choice of Vets1
Serious risk prevention in a tasty chew dogs love

A diagnosis of heartworm disease can be devastating. But prevention is simple with tasty HEARTGARD Plus, the only real-beef chew that prevents heartworm disease, and treats and controls preexisting hookworm and roundworm infections.2


HEARTGARD Plus (ivermectin/pyrantel) is well tolerated. All dogs should be tested for heartworm infection before starting a preventive program. Following the use of HEARTGARD Plus, digestive and neurological side effects have rarely been reported. For more information, contact your veterinarian or click here for full prescribing information.

Our Advantage
Kills & Controls

HEARTGARD Plus not only affects larvae, preventing adult heartworms from developing, it also treats and controls hookworms and roundworms.

Real-Beef Flavor

Dogs like tasty things. So we made HEARTGARD Plus chewables with something they’re sure to love: real beef.2

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1 Chew Per Month

Just one HEARTGARD Plus chewable each month protects your dog all year against heartworm disease.

Inside or out, year-round, all dogs are at risk for heartworm disease no matter where you live in the US4
Infection risk
no data high risk
2018 USA Canine Heartworm
Positive Cases
Total Tested