Woman with dog outdoors
A woman petting her good dog

Prevent Heartworm Disease In Your Dog

HEARTGARD® Plus (ivermectin/pyrantel) prevents the invisible threat of heartworm disease and treats and controls five species of intestinal worms.

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#1 Vet-Recommended1

With more than 2 billion doses prescribed, HEARTGARD® Brand Products are the #1 choice of vets for both their patients and their own dogs.1-3

#1 Dog-Preferred Chew4

Dogs love the only real-beef chew,making monthly dosing easy and delicious. Studies show that more dogs choose it over any other oral heartworm disease prevention.4


HEARTGARD Plus doesn’t just prevent heartworm disease for dogs 6 weeks of age and older, it also treats and controls hookworms and roundworms.†6,7

Veterinarian with a dog Veterinarian with a dog

I have been using HEARTGARD Plus for over twenty years to prevent heartworm disease and control intestinal parasites in my patients. It has been proven to not only be a safe and effective preventive, but it is also a joy to administer as it is a tasty beef chew.

Joseph Zuckerman, DVM
A german shepherd with heart-shaped sunglasses on A german shepherd with heart-shaped sunglasses on
I use HEARTGARD Plus because it has a long-standing reliable reputation for being effective. My dog, Sullivan, a 5-month-old sable German Shephard, loves the best tasting heartworm preventive on the market!”
Gage Blackstone, DVM
Two dogs on the lakeshore Two dogs on the lakeshore
We’ve had our two dogs on HEARTGARD Plus and NexGard (afoxolaner) since we rescued them. Diesel loves traveling and running in the fields. Maxx loves swimming and playing fetch. I always recommend HEARTGARD Plus and NexGard to keep everyone’s pets protected from heartworm disease, fleas and ticks.
Elyce May

Get Prevention From Your Vet

HEARTGARD® Plus chews are #1 vet-recommended for a reason.1 Once your dog has a negative heartworm test and prescription from your vet, you can purchase HEARTGARD Plus chews in clinic or through their online store. Use the search tool below to get started.

Find your vet to ask for HEARTGARD Plus chews

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    Map showing moderate to high infection risks based on USA state geography

    The Risk of Heartworm Disease is Real

    Heartworm disease has been diagnosed in all 50 states.8 And just one bite from an infected mosquito can transmit this potentially deadly disease to your dog. The risk is real. That’s why vets recommend using monthly heartworm disease prevention all year long.

    puppy playing on grass

    Hookworms and Roundworms Are Unexpected Threats

    Your dog can get hookworms and roundworms by stepping in contaminated soil at the park or ingesting them in your own backyard. Luckily, HEARTGARD Plus chews treats and controls three species of hookworms and two species of roundworms. Learn why there’s more to love in the only real-beef chew.

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    A woman holding a puppy in the backyard

    Caring for Your New Pet

    With the help of animal health professionals, we created HealthyHabitsforPets.com, a trustworthy, online resource to help you care for your new pet. From preventive care to dental health and vaccinations, the answers and information you need are available 24/7.
    HEARTGARD and NexGard offer
    HEARTGARD and NexGard offer

    Double the Delight

    Add Flea & Tick Protection to Your Monthly Routine

    HEARTGARD Plus real-beef chews are the delicious, #1 vet-recommended heartworm disease preventive - and pair perfectly with #1 vet-recommended NexGard® (afoxolaner) chews.1,9 And the fact is, dogs love both chews.5,10 That's two tasty chews to double your dog's dosing delight each month.

    IMPORTANT SAFETY INFORMATION: NexGard is for use in dogs only. The most frequently reported adverse reactions include vomiting, itching, lethargy, diarrhea, and lack of appetite. The safe use of NexGard in pregnant, breeding, or lactating dogs has not been evaluated. Use with caution in dogs with a history of seizures or neurologic disorders. For more information, click here for full prescribing information or visit NexGardForDogs.com.


    Protect With Two
    SAVE $60
    HEARTGARD and NexGard offer HEARTGARD and NexGard offer
    Save Big When You Buy Two
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    Get a $60 rebate on your qualifying purchases of either NexGard® (afoxolaner) or a FRONTLINE® Brand Product and HEARTGARD® Plus (ivermectin/pyrantel). Download and present this coupon to your vet. 

    Save on Prevention
    GET $15 BACK
    HEARTGARD Plus for Dogs 26-50lbs Green Box HEARTGARD Plus for Dogs 26-50lbs Green Box
    Get Your Rebate
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    Buy 12 doses of HEARTGARD® Plus (ivermectin/pyrantel) and enjoy a $15 rebate: Simply download the coupon and take it to your vet.

    Fleas and ticks are threats to your dog, too. Pair up HEARTGARD Plus Chews with powerful flea and tick protection.